310 research outputs found

    Against “Revolution” and “Evolution”

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    Abstract Algebra: An Inquiry-Based Approach, Second Edition, Supplemental Material

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    This text is a supplement to Abstract Algebra: An Inquiry-Based Approach, Second Edition. It includes applications of algebra to RSA encryption, check digits, the games of NIM and the 15 Puzzle, and the determination of groups of small order. In addition, reference material that could be useful for some students appears in the appendices, such as background material on functions, methods of proof (including the equivalencies of the Well-Ordering Principle and different versions of mathematical induction), and complex roots of unity. The appendices also contain a complete proof that polynomial rings are rings, a proof of the Fundamental Theorem of Algebra, and a derivation of the formula for solving any cubic equation.https://scholarworks.gvsu.edu/books/1029/thumbnail.jp

    The Darwin of pangenesis

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    Single-Peaked Preferences over Multidimensional Binary Alternatives

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    Single-peaked preferences are important throughout social choice theory. In this article, we consider single-peaked preferences over multidimensional binary alternative spaces—that is, alternative spaces of the form {0, 1}n for some integer n ≄ 2. We show that preferences that are single-peaked with respect to a normalized separable base order are nonseparable except in the most trivial cases. We establish that two distinct base orders can induce the same single-peaked preference order if any only if they differ by a transposition of their two central elements. We then use this result to enumerate single-peaked binary preference orders over a separable base order

    Springbrook: Challenges in developing a long-term, rainforest wireless sensor network

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    We describe the design, development and learnings from the first phase of a rainforest ecological sensor network at Springbrook - part of a World Heritage precinct in South East Queensland. This first phase is part of a major initiative to develop the capability to provide reliable, long-term monitoring of rainforest ecosystems. We focus in particular on our analysis around energy and communication challenges which need to be solved to allow for reliable, long-term deployments in these types of environments

    Assessing technology literacy: The Case for an authentic, project-based learning approach

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    This whitepaper takes a comprehensive look at the research, policies, and practices of technology literacy in K-12 settings in the United States. It builds a research-based case for the central importance of doing as part of technology literacy, meaning more than just being able to answer canned questions on a test. It also explores the current approaches to develop meaningful assessment of student technology literacy at a national, state, and local level, including TechYES

    Deep Proteomic Deconvolution of Interferons and HBV Transfection Effects on a Hepatoblastoma Cell Line

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    Interferons are commonly utilized in the treatment of chronic hepatitis B virus (HBV) infection but are not effective for all patients. A deep understanding of the limitations of interferon treatment requires delineation of its activity at multiple "omic"levels. While myriad studies have characterized the transcriptomic effects of interferon treatment, surprisingly, few have examined interferon-induced effects at the proteomic level. To remedy this paucity, we stimulated HepG2 cells with both IFN-α and IFN-λ and performed proteomic analysis versus unstimulated cells. Alongside, we examined the effects of HBV transfection in the same cell line, reasoning that parallel IFN and HBV analysis might allow determination of cases where HBV transfection counters the effects of interferons. More than 6000 proteins were identified, with multiple replicates allowing for differential expression analysis at high confidence. Drawing on a compendium of transcriptomic data, as well as proteomic half-life data, we suggest means by which transcriptomic results diverge from our proteomic results. We also invoke a recent multiomic study of HBV-related hepatocarcinoma (HCC), showing that despite HBV\u27s role in initiating HCC, the regulated proteomic landscapes of HBV transfection and HCC do not strongly align. Special focus is applied to the proteasome, with numerous components divergently altered under IFN and HBV-transfection conditions. We also examine alterations of other protein groups relevant to HLA complex peptide display, unveiling intriguing alterations in a number of ubiquitin ligases. Finally, we invoke genome-scale metabolic modeling to predict relevant alterations to the metabolic landscape under experimental conditions. Our data should be useful as a resource for interferon and HBV researchers

    The Routledge Handbook of Global Development

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    This Handbook provides a comprehensive analysis of some of the world’s most pressing global development challenges – including how they may be better understood and addressed through innovative practices and approaches to learning and teaching. Featuring 61 contributions from leading and emerging academics and practitioners, this multidisciplinary volume is organized into five thematic parts exploring: changes in global development financing, ideologies, norms and partnerships; interrelationships between development, natural environments and inequality; shifts in critical development challenges, and; new possibilities for positive change. Collectively, the handbook demonstrates that global development challenges are becoming increasingly complex and multi-faceted and are to be found in the Global ‘North’ as much as the ‘South’. It draws attention to structural inequality and disadvantage alongside possibilities for positive change. The Handbook will serve as a valuable resource for students and scholars across multiple disciplines including Development Studies, Anthropology, Geography, Global Studies, Indigenous and Postcolonial Studies, Political Science, and Urban Studies
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